منابع مشابه
TRIM 37 ( tripartite motif - containing 37 )
Hugo: TRIM37 Other names: MUL; KIAA0898; POB1; TEF3 Location: 17q23.2 Local order: Genes flanking TRIM37 oriented from centromere to telomere on 17q23 are: RAD51C, 17q22-q23, D51 homolog C (S. Cerevisiae) PPM1E, 17q23.2, protein phosphatase 1E (PP2C domain containing) TRIM37, 17q22-q23, tripartite motif-containing 37 FAM33A 17q23.2, family with sequence similarity 33, member A PRR11(FLJ11029) 1...
متن کاملThe TRIM family protein KAP1 inhibits HIV-1 integration.
The integration of viral cDNA into the host genome is a critical step in the life cycle of HIV-1. This step is catalyzed by integrase (IN), a viral enzyme that is positively regulated by acetylation via the cellular histone acetyl transferase (HAT) p300. To investigate the relevance of IN acetylation, we searched for cellular proteins that selectively bind acetylated IN and identified KAP1, a p...
متن کاملAnti-HIV-1 Activity of Eight Monofloral Iranian Honey Types
Monofloral Iranian honeys from eight floral sources were analyzed to determine their anti-HIV-1 activities as well as their effects on lymphocyte proliferation. The Peripheral Blood Mononuclear Cells (PBMCs) used in this study were prepared from five healthy volunteers who were seronegative for HIV, HCV, HBV and TB. The anti-HIV-1 activity of eight different honeys was performed by quantitative...
متن کاملAnti-HSV-1 and anti-HIV-1 activity of gallic acid and pentyl gallate.
The synthetic n-alkyl esters of gallic acid (GA), also known as gallates, especially propyl, octyl and dodecyl gallates, are widely employed as antioxidants by food and pharmaceutical industries. The inhibitory effects of GA and 15 gallates on Herpes Simplex Virus type 1 (HSV-1) and Human Immunodeficiency Virus (HIV-1) replication were investigated here. After a preliminary screening of these c...
متن کاملDipyridodiazepinone derivatives; synthesis and anti HIV-1 activity
Ten dipyridodiazepinone derivatives were synthesized and evaluated for their anti HIV-1 reverse transcriptase activity against wild-type and mutant type enzymes, K103N and Y181C. Two of them were found to be promising inhibitors for HIV-1 RT.
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ژورنال
عنوان ژورنال: Journal of General Virology
سال: 2014
ISSN: 0022-1317,1465-2099
DOI: 10.1099/vir.0.057653-0